The late 18th century in the United States witnessed deep disagreements between the two most important figures in the Founding Fathers’ institution, Thomas Jefferson and Alexander Hamilton, which led to the formation of the first two major party organizations in the country: the Federalist Party, led by Hamilton, and the Democratic-Republican Party, led by Jefferson. The research included in its first axis the historical roots of the emergence of American party organizations, leading to the second and third axis in clarifying the main points of difference in the views of the two men towards the country’s foreign and domestic policy, and the method of relationship between the United States of America on the one hand, and Britain and France on the other hand. The two opponents exploited these differences between them for party theorizing, and this was the nucleus of the party organization in the United States of America.